This collection pertains principally to the Cherokees of North Carolina and Oklahoma and to their language, ethnography, folklore, archeology, history, music, etc. Includes Indian studies and correspondence by Gillespie, notes on Indian dances and linguistics, bibliographies, publications of the Archaeological Society of Brigham Young University, and newspaper clippings. Also comprised of materials on: Apache, Calusa, Chippewa, Choctaw, Delaware, Eskimo, Fox, Iroquois, Karankawa, Kuchin, Louchens, Mattaponi, Muskogee, Navajo, Onondaga, Pueblo, Sauk, Seminole, Seneca, Shawnee, Sioux, Slave, Timucua, Tuscarora, Tutelo, and Wyandot. Contains: Gillespie, "A grammar of western dialect of Cherokee language of the Iroquoian family," 1949-1954 (131 pages); "Miscellaneous material on the Cherokee Indians and language"; "Miscellaneous items pertaining to the American Indian."

Trained as an anthropologist under Frank Speck at the University of Pennsylvania, the ethnohistorian George Snyderman (1908- ) spent his career studying Seneca Indian religion, history, and culture. Snyderman edited the previously unpublished diaries of Halliday Jackson and John Phillips, Quaker missionaries to the Senecas in the late 18th and early 19th century. The Snyderman Papers includes a small volume of correspondence, along with manuscripts of works by Snyderman and colleagues, and copies of primary source materials pertaining to Seneca history. Of particular interest is his correspondence with anthropologists William N. Fenton, Merle Deardorff, and Frank Speck and with his Seneca consultant Clara Redeye and her daughter, Helen Harris, and photographs of the Allegany Senecas taken by Fenton and Speck.

An anthropologist and student of Native American cultures, Elisabeth Tooker devoted a long career, much of it as a professor at Temple University, to study of the culture and ethnohistory of the Haudenosaunee of New York State. The Tooker Papers is arranged in six series, and contain her correspondence, subject files, research notes, and both published and unpublished papers.

During the half century leading up to the Second World War, Franz Boas helped to define academic anthropology in the United States. Trained as a geographer at the University of Heidelberg, Boas worked initially on the Inuit of Baffin Island and subsequently on the cultures of the Indians of the Northwest Pacific Coast, becoming a leading figure in American anthropology by the first decade of the twentieth century. As Professor of Anthropology at Columbia University, Boas made significant theoretical contributions to ethnology, linguistics, and physical anthropology, helping to ingrain the four fields approach in his discipline and introducing the concept of cultural relativism into wide currency. He was, as well, a committed Socialist and an ardent opponent of both racism and fascism. This collection includes correspondence that Boas carried on with his colleagues in anthropology, as well as with those in the other social sciences and sciences. This correspondence is rich as a source for twentieth-century historians interested in "radical" social causes, since Boas was a socialist and an outspoken voice for progressive social causes.

Anthropologist and ethnographer Frank Gouldsmith Speck was one of Franz Boas' early graduate students and from 1907 till his death in 1950 spent his career in a variety of positions at the University of Pennsylvania, including its Museum of Archaeology and Anthropology. Unlike most of his contemporaries, Speck chose to study the cultures of Indigenous peoples of eastern North America, especially the Haudenosaunee, Cherokee, and peoples speaking Algonquian languages, such as Anishinaabe, Wabanaki, Innu, Lenape, and other Algonquian peoples within the eastern United States. Speck spent a larger amounnt of time in the field than was typical of most ethnographers, collecting documentary information and physical objects. The Frank G. Speck Papers consist of 15.5 linear feet of Speck's professional correspondence, field notes, lecture notes, and manuscripts of published and unpublished works. The material focuses on the Eastern Woodlands Indians, particularly the Catawba, Cherokee, Creek, Delaware, Houma, Haudenosaunee ("Iroquois"), Labrador Inuit ("Eskimo"), Innu ("Montagnais-Naskapi"), Nanticoke, Penobscot, Powhatan, Algonquian, and Yuchi. The collection is divided into two subcollections: Subcollection 1 is comprised of Speck's research material and correspondence, and Subcollection 2 consists of his manuscripts and related correspondence. The two subcollections were acquired separately by the Society, and were originally cataloged as the Frank G. Speck Papers (572.97 Sp3) and the Frank G. Speck Manuscripts on Native Americans (970.3 Sp3p) respectively.